In today’s FutureCast discussion, RA Capital Principal Zach Scheiner, Senior Associate Becca Silberman, and Managing Partner Peter Kolchinsky talk about the past, present and future of depression therapies and why we’re confident that new uses and forms of old molecules, including psychedelics, will, in the next decade, bring relief to many of those among us who suffer from untreatable depression. Hop in the DeLorean with us at 88 miles per hour as we go 'Back to the Future'.

GoodRx, in collaboration with RA Capital, is surveying patients who have used or even just applied to a PAP. GoodRx is a free price comparison resource that helps Americans find the lowest prescription prices at their local pharmacies. We hope the results of this survey will shed light on PAPs’ role in the healthcare ecosystem as well as shed some light on their strengths and weaknesses.

With all the hype around Covid and monkeypox, it’s easy to forget that viruses aren’t the only infectious game in town. Bacteria caused 3 million worldwide deaths in 2019, at a rate at least five times that of the flu. So why does it still take so long to identify & treat a bacterial infection?

Though its program failed in clinical trials, Nektar kicked off an appreciation for what might be possible with a better IL-2. As other companies carry on with programs in part inspired by Nektar’s early data and vision, we explore failure in biotech, ignoring the naysayers, and the value of carrying on when the odds are slim.

Some might consider Trikafta’s gains to be “good enough” for CF patients. But I think we can do better. And that’s why we’re so excited to introduce the world to Sionna.

Covid has flooded a barren vaccine startup landscape with capital. And that has revealed some valuable lessons for investors, company builders, Congress, and the public.

As more established targeted protein degradation companies produce promising data in the clinic, newcomers have been greeted with sustained enthusiasm from the investment community. Here we revisit a few key intellectual and scientific breakthroughs & focus on molecular glues as an exciting new frontier.

The story of Alexander Fleming is a popular one. As it should be - it’s a good story about one of the most important discoveries in medical history, penicillin. But most people only know the first act of the play.

In this month’s episode of RA TV, we look back at the past year for biotech, examine today’s headlines, and contemplate the future of this pandemic — and maybe the next one.

LENZ Therapeutics CEO Eef Schimmelpennink spoke with RApport about how last year’s acquisition of Pfenex by Ligand gave him a chance to seek out a new challenge, the benefits of breaking the mold, and helping 120 million Americans ditch their reading glasses.

Listen in as RA Capital’s TechAtlas Associates convene to discuss recent Covid-19 news. Learn about the emerging Delta variant, new data from Novavax and CureVac, and the potential association between mRNA vaccines and myocarditis.

Interest in life science technologies and tools is accelerating with the advent of CRISPR and other aspects of synthetic biology. The ability to have a capital efficient way to advance these innovations is very attractive and will help drive innovation.

Listen in as RA Capital’s TechAtlas Associates convene to discuss recent Covid-19 news. Learn about the emerging Delta variant, new data from Novavax and CureVac, and the potential association between mRNA vaccines and myocarditis.

Repatriating the American drug supply is key not just to averting shortages but to restoring and preserving the integrity of generic drugs in America.